Agent Skills
- django-ai-plugins - Django backend agent skills for Django, DRF, Celery, and Django-specific code review.
- sentry-skills - Python-focused engineering skills for code review, debugging, and backend workflows.
- trailofbits-skills - Python-friendly security skills for auditing, testing, and safer backend development.
Orchestration
- autogen - A programming framework for building agentic AI applications.
- crewai - A framework for orchestrating role-playing autonomous AI agents for collaborative task solving.
- dspy - A framework for programming, not prompting, language models.
- hermes-agent - An adaptive AI agent framework that grows with you.
- langchain - Building applications with LLMs through composability.
- pydantic-ai - A Python agent framework for building generative AI applications with structured schemas.
- TradingAgents - A multi-agents LLM financial trading framework.
Data Layer
- instructor - A library for extracting structured data from LLMs, powered by Pydantic.
- llama-index - A data framework for your LLM application.
- mem0 - An intelligent memory layer for AI agents enabling personalized interactions.
Pre-trained Models and Inference
- diffusers - A library that provides pre-trained diffusion models for generating and editing images, audio, and video.
- sglang - A high-performance serving framework for large language models and multimodal models.
- transformers - A framework that lets you easily use pre-trained transformer models for NLP, vision, and audio tasks.
- unsloth - A library for faster LLM fine-tuning and training with reduced memory usage.
- vllm - A high-throughput and memory-efficient inference and serving engine for LLMs.

Deep Learning

Frameworks for Neural Networks and Deep Learning. Also see awesome-deep-learning.

jax - A library for high-performance numerical computing with automatic differentiation and JIT compilation.
keras - A high-level deep learning library with support for JAX, TensorFlow, and PyTorch backends.
pytorch-lightning - Deep learning framework to train, deploy, and ship AI products Lightning fast.
pytorch - Tensors and Dynamic neural networks in Python with strong GPU acceleration.
stable-baselines3 - PyTorch implementations of Stable Baselines (deep) reinforcement learning algorithms.
tensorflow - The most popular Deep Learning framework created by Google.

Machine Learning

Libraries for Machine Learning. Also see awesome-machine-learning.

catboost - A fast, scalable, high performance gradient boosting on decision trees library.
feature_engine - sklearn compatible API with the widest toolset for feature engineering and selection.
h2o - Open Source Fast Scalable Machine Learning Platform.
lightgbm - A fast, distributed, high performance gradient boosting framework.
mindsdb - MindsDB is an open source AI layer for existing databases that allows you to effortlessly develop, train and deploy state-of-the-art machine learning models using standard queries.
pgmpy - A Python library for probabilistic graphical models and Bayesian networks.
scikit-learn - The most popular Python library for Machine Learning with extensive documentation and community support.
spark.ml - Apache Spark's scalable [Machine Learning library](https://spark.apache.org/docs/latest/ml-guide.html) for distributed computing.
TabGAN - Synthetic tabular data generation using GANs, Diffusion Models, and LLMs.
xgboost - A scalable, portable, and distributed gradient boosting library.

Natural Language Processing

Libraries for working with human languages.

General
- gensim - Topic Modeling for Humans.
- nltk - A leading platform for building Python programs to work with human language data.
- spacy - A library for industrial-strength natural language processing in Python and Cython.
- stanza - The Stanford NLP Group's official Python library, supporting 60+ languages.
Chinese
- funnlp - A collection of tools and datasets for Chinese NLP.

Computer Vision

Libraries for Computer Vision.

easyocr - Ready-to-use OCR with 40+ languages supported.
kornia - Open Source Differentiable Computer Vision Library for PyTorch.
opencv - Open Source Computer Vision Library.
pytesseract - A wrapper for Google Tesseract OCR.

Recommender Systems

Libraries for building recommender systems.

annoy - Approximate Nearest Neighbors in C++/Python optimized for memory usage.
implicit - A fast Python implementation of collaborative filtering for implicit datasets.
scikit-surprise - A scikit for building and analyzing recommender systems.

Web Development

Web Frameworks

Traditional full stack web frameworks. Also see Web APIs.

Synchronous
- bottle - A fast and simple micro-framework distributed as a single file with no dependencies.
- django - The most popular web framework in Python.
  - awesome-django
- flask - A microframework for Python.
  - awesome-flask
- pyramid - A small, fast, down-to-earth, open source Python web framework.
  - awesome-pyramid
- fasthtml - The fastest way to create an HTML app.
  - awesome-fasthtml
- masonite - The modern and developer centric Python web framework.
Asynchronous
- litestar - Production-ready, capable and extensible ASGI Web framework.
- microdot - The impossibly small web framework for Python and MicroPython.
- reflex - A framework for building reactive, full-stack web applications entirely with Python.
- robyn - A high-performance async Python web framework with a Rust runtime.
- starlette - A lightweight ASGI framework and toolkit for building high-performance async services.
- tornado - A web framework and asynchronous networking library.

Web APIs

Libraries for building RESTful and GraphQL APIs.

Django
- django-ninja - Fast, Django REST framework based on type hints and Pydantic.
- [django-rest-framework](https://github.com/encode/django-rest-framework) - A powerful and flexible toolkit to build web APIs.
- strawberry-django - Strawberry GraphQL integration with Django.
Flask
- apiflask - A lightweight Python web API framework based on Flask and Marshmallow.
Framework Agnostic
- connexion - A spec-first framework that automatically handles requests based on your OpenAPI specification.
- falcon - A high-performance framework for building cloud APIs and web app backends.
- fastapi - A modern, fast, web framework for building APIs with standard Python type hints.
- sanic - A Python 3.6+ web server and web framework that's written to go fast.
- strawberry - A GraphQL library that leverages Python type annotations for schema definition.
- webargs - A friendly library for parsing HTTP request arguments with built-in support for popular web frameworks.

Web Servers

ASGI and WSGI compatible web servers.

ASGI
- daphne - An HTTP, HTTP/2 and WebSocket protocol server for ASGI and ASGI-HTTP.
- granian - A Rust HTTP server for Python applications built on top of Hyper and Tokio, supporting WSGI/ASGI/RSGI.
- hypercorn - An ASGI and WSGI Server based on Hyper libraries and inspired by Gunicorn.
- uvicorn - A lightning-fast ASGI server implementation, using uvloop and httptools.
WSGI
- gunicorn - Pre-forked, ported from Ruby's Unicorn project.
- uwsgi - A project aims at developing a full stack for building hosting services, written in C.
- waitress - Multi-threaded, powers Pyramid.
RPC
- grpcio - HTTP/2-based RPC framework with Python bindings, built by Google.
- rpyc (Remote Python Call) - A transparent and symmetric RPC library for Python.

WebSocket

Libraries for working with WebSocket.

autobahn-python - WebSocket & WAMP for Python on Twisted and asyncio.
channels - Developer-friendly asynchrony for Django.
flask-socketio - Socket.IO integration for Flask applications.
picows - Fastest WebSocket clients and servers with a frame level interface for the most demanding use-cases.
websockets - A library for building WebSocket servers and clients with a focus on correctness and simplicity.

Template Engines

Libraries and tools for templating and lexing.

jinja - A modern and designer friendly templating language.
mako - Hyperfast and lightweight templating for the Python platform.

Web Asset Management

Tools for managing, compressing and minifying website assets.

django-compressor - Compresses linked and inline JavaScript or CSS into a single cached file.
django-storages - A collection of custom storage back ends for Django.

Authentication

Libraries for implementing authentication schemes.

OAuth
- authlib - JavaScript Object Signing and Encryption draft implementation.
- django-allauth - Authentication app for Django that "just works."
- django-oauth-toolkit - OAuth 2 goodies for Django.
- oauthlib - A generic and thorough implementation of the OAuth request-signing logic.
JWT
- pyjwt - JSON Web Token implementation in Python.
Permissions
- django-guardian - Implementation of per object permissions for Django 1.2+
- django-rules - A tiny but powerful app providing object-level permissions to Django, without requiring a database.

Admin Panels

Libraries for administrative interfaces.

ajenti - The admin panel your servers deserve.
django-grappelli - A jazzy skin for the Django Admin-Interface.
django-unfold - Elevate your Django admin with a stunning modern interface, powerful features, and seamless user experience.
flask-admin - Simple and extensible administrative interface framework for Flask.
flower - Real-time monitor and web admin for Celery.
func-to-web - Instantly create web UIs from Python functions using type hints. Zero frontend code required.
jet-bridge - Admin panel framework for any application with nice UI (ex Jet Django).

CMS

Content Management Systems.

django-cms - The easy-to-use and developer-friendly enterprise CMS powered by Django.
indico - A feature-rich event management system, made @ CERN.
wagtail - A Django content management system.

Static Site Generators

Static site generator is a software that takes some text + templates as input and produces HTML files on the output.

lektor - An easy to use static CMS and blog engine.
nikola - A static website and blog generator.
pelican - Static site generator that supports Markdown and reST syntax.

HTTP & Scraping

HTTP Clients

Libraries for working with HTTP.

aiohttp - Asynchronous HTTP client/server framework for asyncio and Python.
furl - A small Python library that makes parsing and manipulating URLs easy.
httpx - A next generation HTTP client for Python.
requests - HTTP Requests for Humans.
urllib3 - A HTTP library with thread-safe connection pooling, file post support, sanity friendly.

Web Scraping

Libraries to automate web scraping and extract web content.

Frameworks
- browser-use - Make websites accessible for AI agents with easy browser automation.
- crawl4ai - An open-source, LLM-friendly web crawler that provides lightning-fast, structured data extraction specifically designed for AI agents.
- mechanicalsoup - A Python library for automating interaction with websites.
- scrapy - A fast high-level screen scraping and web crawling framework.
Content Extraction
- feedparser - Universal feed parser.
- html2text - Convert HTML to Markdown-formatted text.
- micawber - A small library for extracting rich content from URLs.
- sumy - A module for automatic summarization of text documents and HTML pages.
- trafilatura - A tool for gathering text and metadata from the web, with built-in content filtering.

Email

Libraries for sending and parsing email, and mail server management.

modoboa - A mail hosting and management platform including a modern Web UI.
yagmail - Yet another Gmail/SMTP client.

Database & Storage

ORM

Libraries that implement Object-Relational Mapping or data mapping techniques.

Relational Databases
- django.db.models - The Django ORM.
- sqlalchemy - The Python SQL Toolkit and Object Relational Mapper.
  - awesome-sqlalchemy
- dataset - Store Python dicts in a database - works with SQLite, MySQL, and PostgreSQL.
- peewee - A small, expressive ORM.
- pony - ORM that provides a generator-oriented interface to SQL.
- sqlmodel - SQLModel is based on Python type annotations, and powered by Pydantic and SQLAlchemy.
- tortoise-orm - An easy-to-use asyncio ORM inspired by Django, with relations support.
NoSQL Databases
- beanie - An asynchronous Python object-document mapper (ODM) for MongoDB.
- mongoengine - A Python Object-Document-Mapper for working with MongoDB.
- pynamodb - A Pythonic interface for Amazon DynamoDB.

Database Drivers

Libraries for connecting and operating databases.

MySQL - awesome-mysql
- mysqlclient - MySQL connector with Python 3 support (mysql-python fork).
- pymysql - A pure Python MySQL driver compatible to mysql-python.
PostgreSQL - awesome-postgres
- psycopg - The most popular PostgreSQL adapter for Python.
SQLite - awesome-sqlite
- sqlite-utils - Python CLI utility and library for manipulating SQLite databases.
- sqlite3 - (Python standard library) SQLite interface compliant with DB-API 2.0.
Other Relational Databases
- clickhouse-driver - Python driver with native interface for ClickHouse.
- mssql-python - Official Microsoft driver for SQL Server and Azure SQL, built on ODBC for high performance and low memory usage.
NoSQL Databases
- cassandra-driver - The Python Driver for Apache Cassandra.
- [django-mongodb-backend](https://github.com/mongodb/django-mongodb-backend) - Official MongoDB database backend for Django.
- pymongo - The official Python client for MongoDB.
- redis-py - The Python client for Redis.

Database

Databases implemented in Python.

chromadb - An open-source embedding database for building AI applications with embeddings and semantic search.
duckdb - An in-process SQL OLAP database management system; optimized for analytics and fast queries, similar to SQLite but for analytical workloads.
pickledb - A simple and lightweight key-value store for Python.
tinydb - A tiny, document-oriented database.
ZODB - A native object database for Python. A key-value and object graph database.

Caching

Libraries for caching data.

cachetools - Extensible memoizing collections and decorators.
django-cacheops - A slick ORM cache with automatic granular event-driven invalidation.
dogpile.cache - dogpile.cache is a next generation replacement for Beaker made by the same authors.
python-diskcache - SQLite and file backed cache backend with faster lookups than memcached and redis.

Search

Libraries and software for indexing and performing search queries on data.

django-haystack - Modular search for Django.
elasticsearch-py - The official low-level Python client for Elasticsearch.
pysolr - A lightweight Python wrapper for Apache Solr.

Serialization

Libraries for serializing complex data types.

marshmallow - A lightweight library for converting complex objects to and from simple Python datatypes.
msgpack - MessagePack serializer implementation for Python.
orjson - Fast, correct JSON library.

Data & Science

Data Analysis

Libraries for data analysis.

General
- aws-sdk-pandas - Pandas on AWS.
- datasette - An open source multi-tool for exploring and publishing data.
- desbordante - An open source data profiler for complex pattern discovery.
- ibis - A portable Python dataframe library with a single API for 20+ backends.
- modin - A drop-in pandas replacement that scales workflows by changing a single line of code.
- pandas - A library providing high-performance, easy-to-use data structures and data analysis tools.
- pathway - Real-time data processing framework for Python with reactive dataflows.
- polars - A fast DataFrame library implemented in Rust with a Python API.
Financial Data
- akshare - A financial data interface library, built for human beings!
- edgartools - Library for downloading structured data from SEC EDGAR filings and XBRL financial statements.
- lumibot - Algorithmic trading framework for backtesting and live deployment across stocks, options, crypto, futures, and forex.
- openbb - A financial data platform for analysts, quants and AI agents.
- yfinance - Easy Pythonic way to download market and financial data from Yahoo Finance.

Data Validation

Libraries for validating data. Used for forms in many cases.

cerberus - A lightweight and extensible data validation library.
jsonschema - An implementation of JSON Schema for Python.
pandera - A data validation library for dataframes, with support for pandas, polars, and Spark.
pydantic - Data validation using Python type hints.
voluptuous - A Python data validation library primarily intended for validating data from untrusted sources.

Data Visualization

Libraries for visualizing data. Also see awesome-javascript.

Plotting
- altair - Declarative statistical visualization library for Python.
- bokeh - Interactive Web Plotting for Python.
- bqplot - Interactive Plotting Library for the Jupyter Notebook.
- matplotlib - A Python 2D plotting library.
- plotly - Interactive graphing library for Python.
- plotnine - A grammar of graphics for Python based on ggplot2.
- pygal - A Python SVG Charts Creator.
- pyqtgraph - Interactive and realtime 2D/3D/Image plotting and science/engineering widgets.
- seaborn - Statistical data visualization using Matplotlib.
- ultraplot - Matplotlib wrapper for publication-ready scientific figures with minimal code. Includes advanced subplot management, panel layouts, and batteries-included geoscience plotting.
- vispy - High-performance scientific visualization based on OpenGL.
Specialized
- cartopy - A cartographic python library with matplotlib support.
- pygraphviz - Python interface to Graphviz.
Dashboards and Apps
- gradio - Build and share machine learning apps, all in Python.
- streamlit - A framework which lets you build dashboards, generate reports, or create chat apps in minutes.

truncated — full list on GitHub

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